Journal: Cancer discovery
Article Title: PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage
doi: 10.1158/2159-8290.CD-18-0083
Figure Lengend Snippet: (A) Phosphorylation of Pten was detected using the phospho-(Ser/Thr) ATM/ATR substrate antibody (pS/TQ) upon etoposide treatment. Immunoblot (IB) analysis of anti-Pten immunoprecipitations (IPs) and whole cell lysates (WCL) derived from NIH3T3 cells treated with 30 μM etoposide as indicated time points before harvesting.
Article Snippet: Anti-PTEN (sc-7974), anti-MDC1 (sc-27737), anti-p53 (sc-6243/126), anti-ATM (sc-23921), anti-ATR (sc-1887), anti-pCREB (sc-81486), anti-Lamin A/C (sc-7293), anti-GAPDH (sc-47724), anti-BRCA1 (sc-6954), anti-53BP1 (sc-22760), anti-Rad51 (sc-398587), anti-HA (sc-805) and anti-GST (sc-459) antibodies were obtained from Santa Cruz.
Techniques: Western Blot, Derivative Assay